Search results for "design [electronics]"
showing 10 items of 505 documents
Regole per costruire in campagna
2014
Il saggio illustra l'esperienza didattica di un Laboratorio di Progettazione di primo anno del Corso di Laurea in Architettura della Università di Palermo il cui docente è Michele Sbacchi. Il tema affrontato è il progetto di una casa unifamiliare nella campagna. La didattica è sviluppata in modo da fare scaturire il progetto come un ragionamento a partire dalla osservazione del contesto, nella presupposizione di uno scopo. La didattica è quindi improntata a indurre a una procedura corretta piuttosto che al confezionamento di un prodotto. I progetti svolti individualmente, mettono in scena rigore compositivo e completa derivazione dal contesto. Description of first-year architectural design …
Design, synthesis, biological evaluation and molecular modelling of substituted pyrrolo[2,1-a]isoquinolinone derivatives: discovery of potent inhibit…
2021
We report here the design, synthesis and biological evaluation of a new series of substituted pyrrolo[2,1-a]isoquinolin-3-one derivatives, some of which have strong inhibitory activity against both AChE and BChE enzymes. The design of these new inhibitors was carried out taking rivastigmine as the starting structure. Thus, on the basis of an exhausting molecular modeling study using combined techniques (docking, dynamic molecular simulations and QTAIM calculations), we obtained new ligands possessing stronger inhibitory effects than rivastigmine, the reference compound. QTAIM analysis gave us detailed information about the molecular interactions stabilizing the different ligand–enzyme compl…
Design, synthesis and antiproliferative activity of methyl 4-Iodo-1-β-D-ribofuranosyl-pyrazole-3-carboxylate and related compounds
1996
Abstract In a SAR study on azole-related nucleosides we have designed some pyrazole-nucleoside analogs characterised, for the first time, by a carboxylic ester moiety. 4-Iodo-1-β-D-ribofuranosyl-pyrazole-3-carboxylate showed a wide spectrum of antiproliferative activity and a particularly low cytotoxicity against resting PBL, being, unlike the other azole nucleosides, more active than the corresponding primary amide.
ChemInform Abstract: Photochemical Electrocyclization of 3-Vinylindoles (VIII) to Pyrido[2,3-a]- (IX), Pyrido[4,3-a]- (X) and Thieno[2,3-a]-carbazole…
2009
Investigating the Reliability of Stationary Design Rainfall in a Mediterranean Region under a Changing Climate
2023
Extreme rainfall events have been more frequent in recent decades, potentially as a climate change effect. This has been leading to a higher risk of the failure of existing hydraulic infrastructures, and to a higher awareness regarding the unreliability of design rainfall calculated with reference to historical data recorded in the last century. With this in mind, the present study questions the stationary assumption of the rainfall Depth–Duration–Frequency curves commonly used in Sicily, the biggest island of the Mediterranean Sea. Quantiles derived from the most up-to-date regional method, regarding Sicily, based on observations in the period 1928–2010, have been compared with those extra…
From Design to Service Design, and Co-production
2019
This paper was presented at the KU Leuven Public Governance Institute IIAS Study Group on ‘Coproduction of Public Services’ seventh annual conference, Leuven, Belgium, 28 May 2019.
Fashion Technology : What Are the Limits of Emerging Technological Design Thinking?
2021
Designing intelligent technologies is a multidisciplinary process. From this perspective, fashion has continued to be an under explored dimension of technology design. While there persistently are connections between the term fashion and the clothing design industry, an historical and sociological approach to fashion reveals a much deeper and permeating understanding of the notion and its implications across the technological world. During recent popular developments, the interrelationship between fashion as a concept and technology as components and proponents of fashion – technology as fashion promoter (think of Tiktok, Instagram, Facebook and even LinkedIn for example), and technology as…
Responsible cognitive digital clones as decision-makers: A design science research study
2022
This study uses a design science research methodology to develop and evaluate the Pi-Mind agent, an information technology artefact that acts as a responsible, resilient, ubiquitous cognitive clone – or a digital copy – and an autonomous representative of a human decision-maker. Pi-Mind agents can learn the decision-making capabilities of their “donors” in a specific training environment based on generative adversarial networks. A trained clone can be used by a decision-maker as an additional resource for one’s own cognitive enhancement, as an autonomous representative, or even as a replacement when appropriate. The assumption regarding this approach is as follows: when someone was forced t…
Diffusion of digital culture: analysis of the Internet forum of a MOOC
2017
When MOOCs are increasing all over the world as a mean for improving the diffusion of culture and science, it is interesting to observe how those MOOCS build communities of knowledge, and which is the impact of those communities on the acquisition of knowledge. In this article, we present the principles of design of the MOOC Digital & Culture Writing that aims to spread digital culture. Then, we analyse the messages posted on forums by the related community, and the cognitive process to which they refer. Posts analysis reveals reflexivity processes when participants are writing on forums. It appears that reflexivity cognitive processes are at the heart of both social interaction and digital…
Designing and investigating pedagogical scripts to facilitate computer-supported collaborative learning
2008
Computer-supported collaborative learning (CSCL) appears to provide a promising social approach to foster learning. On the other hand, recent studies have indicated that when learners are left on their own, it is often difficult for teams to engage in productive interactions. Therefore, the use of collaboration scripts as instructional support has been presented as a possibility to trigger productive collaborative activities. This study provides knowledge of collaboration scripts as a pedagogical method to facilitate group processes in virtual environments in authentic educational contexts. The findings indicate that scripts as external support can help students proceed in solving learning …